PhD program
Biotechnology

Biotechnology

QUALIFICATION

  • Scientific and pedagogical direction - Doctor of Philosophy (PhD)

MODEL OF GRADUATING STUDENT

LO1: critically evaluate modern scientific achievements and problems of biotechnology, predicting new trends in the use of biotechnological processes;
LO2: use deep system knowledge and modern methodological approaches in the study of biotechnology objects with the aim of applying this data in bioengineering, medical diagnostics, environmental monitoring, pharmaceuticals, production of new food products, etc.
LO3: generate ideas for creating new technologies for producing innovative products that are promising for biomedicine, bioinformatics, agriculture, ecology, nanotechnology, the food industry, etc. taking into account biosafety and bioethical standards.
LO4: carry out original research and development work characterized by academic integrity, based on modern knowledge, theories and research methods in the field of biotechnology, as well as interdisciplinary research (with subsequent commercialization of the results obtained);
LO5: critically evaluate work results using modern information technologies, demonstrating a high level of computer literacy;
LO6: present the results of the work performed in the form of reports, presentations, scientific papers and publications in rating publications, substantiating and defending their point of view in the scientific community at international scientific forums, conferences and seminars, including in a foreign language.
LO7: carry out pedagogical activities in the main educational programs of higher and postgraduate education in the field of biological sciences, taking into account the principles of student-centered learning and assessment, using innovative methods and information technologies, developing regulatory documents regulating the content, design and educational and methodological support of the educational program..
LO8: apply the complex of acquired knowledge and skills in organizational activities, management of scientific or production teams on the basis of ethical and legal standards, establishing collaboration with internal and external scientific schools/centers for the practical implementation of research results;
LO9: carry out an examination of scientific projects and results of scientific research, scientific articles, regulatory documents in the field of science and education, as well as scientific and methodological documentation, participating in scientific and methodological work as part of methodological commissions and councils of all levels

Program passport

Speciality Name
Biotechnology
Speciality Code
8D05105
Faculty
Biology and Biotechnology

disciplines

Academic writing
  • Number of credits - 2
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop practical skills of writing academic texts for doctoral students in order to present the results of their work in the form of reports, reviews, scientific reports and publications in rating publications indexed in Scopus that meet the criteria of non-predatory publications. Within the discipline, doctoral students improve their skills in analyzing and presenting of scientific information in various forms.

Development and Production of Biotechnological Products
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to develop and use modern technologies for the production of biotechnological products for: healthcare, agriculture, environmental protection, food and processing industries. The discipline studies: modern methods used for the production of new biotechnological products, prospects for the development of modern biotechnological production, as well as methodological approaches and ways to solve production problems of modern industrial biotechnology.

Methods of Molecular Biotechnology
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to apply modern molecular methods of biochemistry, biophysics, molecular biology and genetics, which are widely used in biotechnology. The discipline considers: experimental approaches to studying biotechnology objects at the molecular level; advances in the application of molecular methods in the study of biological objects; achievements in the study of the structural and functional organization of biological objects using molecular methods.

PhD thesis writing and defence
  • Number of credits - 12
  • Type of control - Докторская диссертация
  • Description - The main purpose of "PhD thesis writing and defence": of a doctoral dissertation is the formation of the doctoral students' ability to disclose the content of research work for the defense of the thesis. During the study of course, doctoral student's should be competent in: 1. to substantiate the content of new scientifically grounded theoretical and experimental results that allow to solve a theoretical or applied problem or are a major achievement in the development of specific scientific directions; 2. explain the assessment of the completeness of the solutions to the tasks assigned, according to the specifics of the professional sphere of activity; 3. they can analyze alternative solutions for solving research and practical problems and assess the prospects for implementing these options; 4. apply the skills of writing scientific texts and presenting them in the form of scientific publications and presentations. 5. to plan and structure the scientific search, clearly highlight the research problem, develop a plan / program and methods for its study, formalize, in accordance with the requirements of the State Educational Establishment, the scientific and qualification work in the form of a thesis for a scientific degree Doctor of Doctor of Philosophy (PhD) on specialty «8D07502 – Standardization and certification (by industry)». During the study of the discipline doctoral student will learn following aspects: Registration of documents for presentation of the thesis for defense. Information card of the dissertation and registration-registration card (in the format Visio 2003). Extract from the minutes of the meeting of the institution, in which the preliminary defense of the thesis took place. Cover letter to the Higher Attestation Commission. Expert conclusion on the possibility of publishing the author's abstract. Expert opinion on the possibility of publishing a dissertation. Minutes of the meeting of the counting commission. Bulletin for voting. A shorthand record of the meeting of the dissertational council. List of scientific papers. Response of the official opponent. A review of the leading organization. The recall of the scientific adviser.

Scientific Research methods
  • Number of credits - 3
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to form the ability to apply modern methods and methodologies of scientific research when performing a doctoral dissertation. Here are considered: methods and methodologies of scientific research; modern experimental approaches to the scientific research of a doctoral student; stages and principles of planning a scientific experiment.

Data for 2021-2024 years

disciplines

Bioavailability, Biotransformationof Xenobiotics and Natural Polymers
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to form the ability of undergraduates to analyze the theoretical foundations of the toxic effects of xenobiotics and their metabolic pathways in a living organism. The course includes the study of the interaction of xenobiotics or products of its biotransformation in the body with the structural elements of Biosystems. As well as within the discipline the General characteristics of separate groups of xenobiotics, their main phases of biotransformation and biochemical mechanisms of xenobiotics biodegradation are considered.

Bioconversion technologies for processing raw materials for food production
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to use enzymatic processes of plant, animal and microbial raw materials to obtain food products. The discipline studies: biocatalytic processes of transformation of raw materials into feed and food products; technologies and equipment for producing environmentally friendly products, dietary supplements for food and feed purposes; genetic engineering methods for food biotechnology, taking into account biosafety standards.

Bioenergy of phototrophic microorganisms
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to use the biotechnological potential of phototrophic microorganisms to produce various types of biofuels. The discipline studies: the problems of searching for alternative energy sources, the possibility of using microalgae and cyanobacteria in bioenergy, methods and conditions for obtaining biofuel based on the use of phototrophs, the influence of stress factors on the energy productivity of microalgae.

Bioethics and biosafety in biotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to use ethical standards and biosafety problems arising in the development of modern biotechnological practice. The discipline studies: ethical aspects of the creation and use of transgenic plants and animals, moral and legal aspects of modern reproductive technologies; risk factors of genetic engineering activities for the environment and health, legal framework for regulating biosafety.

Bioinformatics in bioengineering
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The aim of the course is to form the ability to use bioinformatics technologies in animal, plant and microorganism bioengineering. During the study of course, students should be able to: 1. apply modern approaches characteristic of bioengineering and bioinformatics to solve problems facing both fundamental and applied science; 2. use the acquired knowledge and professional skills for competent analysis of a large amount of information and scientific data on biological objects (decrypted genomes, spatial structures of biomolecules, interaction of biological objects); 3. understand the basic principles of modified or new biological objects designing 4. use methods of bioinformatics and bioengineering in molecular diagnostics, selection of new targets for drugs, medical and genetic research; 5. master the methods of observation, description, identification and scientific classification of biological objects; Course content: The use of information and computer technology in the genetic engineering of organisms. Molecular basis of cell culture. The study of structural and functional features of the mitochondrial and chloroplast genomes. Development of methods for molecular diagnostics and selection of new targets for drugs. The study of bioinformatics approaches to solving problems of biotechnology, acquaintance with new methods of preserving natural resources, plant and animal life.

Bioinformatics in socially significant diseases
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to familiarize students with the IT-technologies of searching for potential drugs and targets for the treatment of socially significant diseases. Upon completion of the study of this discipline doctoral students will be able to: 1. evaluate and predict current trends, trends and patterns in the development of bioinformatics; 2. to process and further analyze a large body of information on biological objects (decrypted genomes, spatial structures of biomolecules, interaction of biological objects); 3. to develop methods of molecular diagnostics and selection of new targets for drugs based on informational studies of genomes; 4. use bioinformatics methods in molecular diagnostics of socially significant diseases; 5. apply modern information technologies and specialized programs for processing the obtained data and their bioinformatics analysis; Within the discipline are considered: the use of databases of relevant substances, the combination of their structures using computer technologies for the introduction of candidates for drugs, the study of chemo informatics, the use of a virtual screening database of libraries.

Bioinformatics in systems biotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to study complex interactions in living systems using computer and information technologies.The discipline studies: modern methods (transcriptomics, metabolomics, proteomics, etc.) of computer and information technologies for studying interactions between the constituent parts of biological systems; studying the mechanisms of formation of functions and system properties as a result of these interactions.

Bionanotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to use knowledge and skills in the field of bionanotechnology for medicine, the food industry, etc. The discipline studies: bionanostructures and their properties; creation of various devices using bionanoobjects; connection between science and production based on bionanotechnologies; modern directions of nanobiotechnology development; use of DNA in nanobiotechnology; biosensors and their use.

Biotechnologies for the transformation of toxicants and natural polymers
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to develop the ability to evaluate metabolic pathways and specific systems in diverse groups of microorganisms responsible for the transformation of toxic compounds and natural polymers. The discipline examines modern ideas about aerobic, anaerobic and reductive biotransformation due to metabolic processes, as well as developments in the field of monitoring catabolic genes of microorganisms in the context of modern biotechnology.

Commercial biotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to form the ability of doctoral students to use knowledge in the field of commercial biotechnology. Upon completion of the study of this discipline doctoral students will be able to: 1. demonstrate systemic knowledge and understanding of the current state, methods and directions of development of commercial biotechnology on a national and transnational scale; 2. systematize modern approaches for creating, developing and analyzing the activities of commercial biotechnology companies, including in the context of the student environment; 3. choose the strategy and tactics of conducting commercial transactions with products of biotechnology to overcome risk factors and inept administrative actions, as well as other factors affecting the productivity of biotechnological processes. 4. apply the most effective alternative methods of commercial biotechnology; 5. forecast further breakthroughs in commercial biotechnology. The following topics are covered within the framework of this discipline: the study of commercially attractive biotechnological products, the conditions for their production, marketing, marketing, and the derivation of a derivative of innovative products; overview of major transnational and national commercial biotech industries; the main rules in the process of establishing and developing a commercial biotechnology company; profitable biotech business as an integral and advanced part of biotechnology.

Data analysis in biotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The discipline aims to develop the ability to conduct complex analysis and use the results for scientific research and commercial projects in biotechnology. Statistical methods of data analysis, including big data, methods for analyzing data from genomic, proteomic and metabolomic studies, machine learning for classification, prediction and optimization of biotechnological processes will be considered.

Dispersive Analysis in Biotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Upon completion of the study of this discipline doctoral students will be able to: 1. plan and implement a variance analysis of qualitative traits; 2. demonstrate skills in collecting and processing experimental data required in engineering practice and research activities; 3. demonstrate the skills of mathematical modeling of production problems, search for their optimal solution, analysis and evaluation of the results obtained; 4. apply the basic techniques of mathematical modeling in solving problems of different nature; 5. demonstrate the skills of conducting the difference method, analysis of variance of single-factor and multifactor experiment, correlation and regression analyzes; Within the discipline are considered: the statistical impact of one or several factors on the resultant feature; various types and modifications of analysis of variance, methods for assessing the strength of influence and reliability of influences of factors; estimation of the difference between private averages and private shares; forecasting the development of the trait under a given set of conditions.

Genetic engineering therapy
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The discipline aims to develop the ability to analyze the modern gene technologies’ achievements used to treat hereditary and acquired diseases. Genome editing and genetic engineering technologies, mechanisms and strategies for delivering genes into cells, target diseases for gene therapy, ethics and safety of genetic engineering will be considered.

Genomics and Gene Diagnostics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to form the ability to demonstrate a systematic understanding of the main tasks of genodiagnostics and genomics. By the end of the module, students will be able to: 1. demonstrate a systematic understanding of the main tasks of genodiagnostics and gene therapy; 2. critically evaluate the practical and theoretical foundations of methods for analyzing genomes; 3. plan and conduct integral genodiagnostic and general laboratory research; 4. correctly operate the instruments and materials necessary for carrying out genome research. 5. predict and analyze the results of a molecular genetic experiment Within the framework of this discipline, the latest achievements of molecular genetics in the field of genomics and gene diagnostics are considered, which provide, among other things, understanding of the biochemical, physiological, molecular and other key processes occurring in a human body. The discipline provides knowledge of mutation detection methods, molecular diagnostic features, state and prospects of gene therapy of various hereditary diseases.

Metabolic engeneering
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to use the characteristics of metabolism to create new organisms with directionally modified metabolic transformations of substrates into target products. The discipline studies: specific features of the metabolism of various organisms; methods for targeted changes in the metabolism of relevant microorganisms to obtain the target product; Strategies for metabolic engineering: computer analysis, omics data, optimization of metabolic pathways.

Modern Methods of Research of Genetically Modified Raw Materials
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to use methods for the detection and analysis of genetically modified organisms and products derived from them. The discipline studies methods for detecting GMРs: various types of PCR, microarray technology, loop isothermal amplification, capillary gel electrophoresis, enzyme-linked immunosorbent assay, next generation sequencing, search for markers of new GMРs, regulations governing the admission, trade and labeling of GM food products.

Modern Problems of Photobiotechnology
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to use knowledge about the biology of phototrophic microorganisms to solve biotechnological problems. The discipline examines: features of the use of phototrophs in the production of proteins, lipids, dyes, food additives; in the production of bioplastics, as biofertilizers and animal feed, in biomonitoring of aquatic ecosystems, in bionanotechnology. Production of biofuels based on phototrophic microorganisms.

Molecular Biology of Microorganozms
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to form the ability to demonstrate systemic knowledge about the molecular characteristics of microbial systems and the processes they carry out. As a result of studying the discipline, the doctoral student will be able to: 1. demonstrate a systematic understanding of the molecular features of microbial systems; 2. explain the molecular processes occurring in microbial systems; 3. select and develop technologies for the production of microbial synthesis; 4. evaluate the prospects for the use of microbial systems in molecular biotechnology; 5. analyze the prospects for the use of microbial systems in molecular biotechnology; Specific topics includes: structural and functional organization of micro-organisms, the practical use of microorganisms in biotechnological processes to obtain products through microbial systems, the molecular basis of microbial synthesis, the prospects for the use of microbial systems in molecular biotechnology; metagenomic analysis of microbial communities.

Molecular biotechnology of pro- and eukaryots
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The goal of the discipline is to develop the ability to use the organizational features of pro- and eukaryotes to obtain target products. The discipline studies: the production and introduction of hybrid DNA into the cells of microorganisms, plants and animals; introduction of computer methods for monitoring technological modes that allow maximum realization of the beneficial properties of cells; use of recombinant technologies for the design of biomolecules with specified parameters.

Nutrient Potential of Food Raw Materials
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline - to form the ability to demonstrate a holistic knowledge of the system of food raw materials and its potential. At the end of the course the doctoral students will have the following abilities: 1. demonstrate systemic knowledge of the processes of biotechnological transformation of the properties of food raw materials; 2. explain the processes occurring in food raw materials during storage and processing; 3. analyze the processes that occur with food substances when ingested; 4. evaluate the principles, methods and approaches of quantitative and qualitative analysis of structure formation in food systems; 5. predict chemical, physical-chemical, colloidal, biochemical transformations in food raw materials; The discipline considers: sources and methods of processing food raw materials using biotechnological methods. Food raw materials as a multicomponent, multifunctional, biologically active system. Biotechnological and biogenic potential of food raw materials. Functional and technological properties of raw materials, food additives and food systems.

Phythopathology and technologies of plants defence
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline is to study and apply in practice modern technologies for protecting plants from pathogens. The discipline covers: classification of plant diseases; pathogens of plant diseases (viruses, viroids, bacteria), their characteristics; modern methods of protecting plants from pathogens; biological protection of plants from phytopathogens; technologies for producing multifunctional drugs with various spectrums of action.

Proteomical Technologies
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The aim of the course is to study the prospects of using modern proteomic technologies in medicine, pharmacology, and industrial production. As a result of studying the discipline, doctoral students will be able to: 1. demonstrate a systematic understanding of modern methods of studying proteomes; 2. argue the possibilities of using proteomic technologies for diagnostic purposes; 3. apply bioinformatic technologies for processing the results of proteomic experiments on the modeling of structure, dynamics, protein function and complex nanomolecular systems. 4. substantiate the possibilities of using proteomic technologies for control over the quality of food products; 5. predict and search for biomarkers for diagnostics, prognosis of the course or monitoring of therapy of socially significant diseases with the help of proteomic technologies; Course content: Proteomics: new technologies in biology and medicine. Use of proteomic technologies for creation of methods for diagnosis of various diseases, to search for diagnostic markers of disease. Different approaches in the use of proteomic technologies to identify biomarkers. Stages of proteomic analysis. Technology development of proteomic analysis in the formation of instrumentation for molecular diagnostics. Using proteomics technology to create quality control methods of various food products. Proteomic technologies in the field of personalized medicine for the development of medical diagnostic equipment, the creation of new medicines, diagnosis and treatment of socially significant and rare diseases.

Theoretical Basis of Nutritional Biochemistry
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline - to form the ability to demonstrate knowledge in the field of nutrition biochemistry, aimed at the organization of balanced nutrition and healthy lifestyles. Upon completion of the study of this discipline, doctoral students will be able to: 1. demonstrate systemic knowledge about the functions of nutritional substances and their role for the human body; 2. evaluate the principles of rational human nutrition for the preservation of his health; 3. plan and implement modern methods of researching the composition and quality of food. 4. сritically analyze the consequences of nutrient intake in excess or inadequate quantities 5. substantiate the basic principles of rational nutrition. The discipline includes: modern scientific theories of nutrition; principles of nutrition; calorie diet; nutritional value of food. Features of the metabolism of individual substances. Principles of rationing. Nutrition culture of a healthy person.

Data for 2021-2024 years

INTERNSHIPS

Pedagogical
  • Type of control - Защита практики
  • Description - Formation of practical, educational-methodical skills of conducting lectures, seminars, creatively apply scientific, theoretical knowledge, practical skills in teaching activities, conduct training sessions in the disciplines of the specialty; own modern professional techniques, methods of training, use in practice the latest theoretical, methodological advances, make educational, methodological documentation.

Research
  • Type of control - Защита практики
  • Description - The purpose of the practice: gaining experience in the study of an actual scientific problem, expand the professional knowledge gained in the learning process, and developing practical skills for conducting independent scientific work. The practice is aimed at developing the skills of research, analysis and application of economic knowledge.

Data for 2021-2024 years