PhD program
Genetics

Genetics

QUALIFICATION

  • Scientific and pedagogical direction - Doctor of Philosophy (PhD)

MODEL OF GRADUATING STUDENT

1. Analyze the features of the genetic organization and the mechanisms for the implementation of genetic information depending on the functioning of the organism, including in the evolution;
2. Assess the main trends in the development of advanced ideas and new methods in genetics to solve genetic and genetic engineering problems;
3. Carry out scientific research based on the use of advanced technologies in general and molecular genetics to solve actual problems in biology, medicine, biotechnology and ecology;
4. Implement new methods of molecular genetic research with enhanced analytical and clinical diagnostic reliability, interpreting the results of genetic research to develop a working hypothesis of a scientific problem;
5. Summarize the key principles of the modern theory and methodology of genetics, molecular biology and genetic engineering for the develop and conduct of interdisciplinary research;
6. Build research, manufacturing and teaching activities on the basis of ethical and legal norms in relations between people and in the relations of living organisms on the basis of the bioethics principles;
7. Integrate molecular genetic results obtained during the implementation of research projects and thesis in the educational process and work experience;
8. Develop proposals for the modernization of breeding-genetic and genetic engineering activities in the centers and laboratories of biological, medical, agricultural profile;
9. Develop educational-methodical complexes of disciplines and teach theoretical and applied courses based on a student-oriented approach using digital technologies, interactive methods, forms and means of education for solving educational problems of full-time, dual, distance and inclusive education;
10. Find the application of their professional abilities in the field of modern genetic science in the context of international cooperation, interdisciplinarity and business incubation based on pilot and long-term genetic research algorithms, promoting the development of science and society

Program passport

Speciality Name
Genetics
Speciality Code
8D05104
Faculty
Biology and Biotechnology

disciplines

Academic writing
  • Number of credits - 2
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose: to develop practical skills of writing academic texts for doctoral students in order to present the results of their work in the form of reports, reviews, scientific reports and publications in rating publications indexed in Scopus that meet the criteria of non-predatory publications. Within the discipline, doctoral students improve their skills in analyzing and presenting of scientific information in various forms.

Genetic Evolution Mechanisms
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Aim of discipline: to form the ability to explain the genetic mechanisms of the organic evolutionary process and the relationship of the human-nature-society system. In studying the discipline, the following aspects will be addressed: basic principles of organizing life; levels of organization of life: molecular genetic, ontogenetic, population-specific, biogeocenotic levels of organization of life; the genetic basis of microevolution; elementary evolutionary factors: mutations, population waves, isolation, gene drift, migration, natural selection; adaptaciogenesis; molecular and genetic mechanisms of progressive evolution; system man-nature-society.

Genome editing technologies
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to develop the ability to demonstrate a systematic understanding of promising genome editing technologies and the possibility of their application to solve practical problems. The course covers methods using ZFN or zinc finger (site-specific nuclease) systems; TALEN (chimeric nuclease constructs), CRISPR/Cas9 method and other genome editing methods; assessment of the safety and effectiveness of approved editing methods.

Molecular evolution and phylogenetics
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Aim of discipline to develop the ability to conduct advanced research in the field of molecular evolution and phylogenetics using the latest methods and technologies. It will consider: patterns and mechanisms of changes in genetic macromolecules (DNA, RNA, proteins) in the process of evolution, the evolution of genes and organisms; molecular phylogenetic analysis, genetic foundations of macroevolutionary changes, epigenetic changes in evolutionary processes.

Molecular mechanisms of heredity and variability
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Aim of discipline: to form the ability to analyze the development trends of modern genetics and molecular biology in order to develop new scientific and methodological approaches to studying the molecular mechanisms of heredity and variability. In studying the discipline, the following aspects will be addressed: modern advances in studying the domain organization of RNA and evolutionary aspects at the molecular level, regulation of phage and viral genes; bacterial genome regulatory pathways; mobile genetic elements and their regulation, principles of domain formation, independent, cooperative and integral regulation of eukaryotic genes, cluster genes, and their regulation; methods of differential gene expression, genome mapping, the use of GMOs, their certification and prevention of undesirable effects, gene therapy as a practice of gene regulation.

PhD thesis writing and defence
  • Number of credits - 12
  • Type of control - Докторская диссертация
  • Description - The main purpose of "PhD thesis writing and defence": of a doctoral dissertation is the formation of the doctoral students' ability to disclose the content of research work for the defense of the thesis. During the study of course, doctoral student's should be competent in: 1. to substantiate the content of new scientifically grounded theoretical and experimental results that allow to solve a theoretical or applied problem or are a major achievement in the development of specific scientific directions; 2. explain the assessment of the completeness of the solutions to the tasks assigned, according to the specifics of the professional sphere of activity; 3. they can analyze alternative solutions for solving research and practical problems and assess the prospects for implementing these options; 4. apply the skills of writing scientific texts and presenting them in the form of scientific publications and presentations. 5. to plan and structure the scientific search, clearly highlight the research problem, develop a plan / program and methods for its study, formalize, in accordance with the requirements of the State Educational Establishment, the scientific and qualification work in the form of a thesis for a scientific degree Doctor of Doctor of Philosophy (PhD) on specialty «8D07502 – Standardization and certification (by industry)». During the study of the discipline doctoral student will learn following aspects: Registration of documents for presentation of the thesis for defense. Information card of the dissertation and registration-registration card (in the format Visio 2003). Extract from the minutes of the meeting of the institution, in which the preliminary defense of the thesis took place. Cover letter to the Higher Attestation Commission. Expert conclusion on the possibility of publishing the author's abstract. Expert opinion on the possibility of publishing a dissertation. Minutes of the meeting of the counting commission. Bulletin for voting. A shorthand record of the meeting of the dissertational council. List of scientific papers. Response of the official opponent. A review of the leading organization. The recall of the scientific adviser.

Scientific Research methods
  • Number of credits - 3
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to form the ability to apply modern methods and methodologies of scientific research when performing a doctoral dissertation. Here are considered: methods and methodologies of scientific research; modern experimental approaches to the scientific research of a doctoral student; stages and principles of planning a scientific experiment.

Data for 2021-2024 years

disciplines

Agricultural genetics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Discipline aims to form the ability to conduct advanced scientific research and apply the latest genetic methods and technologies to create new varieties of plants and animal breeds. It will be considered: organization and technique of breeding process, intraspecific and interspecific hybridization, introgression, mutagenesis and polyploidy in plant breeding, breeding of heterozygous hybrids, molecular-genetic methods of breeding; association mapping.

Applied genetics and genomics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Discipline aims to develop the ability to conduct advanced scientific research and apply modern methods of applied genetics and genomics to solve complex problems in various fields of genetics, biology and medicine. It will consider: new generation sequencing (NGN) methods, methods for obtaining transgenic plants, animals and cloning; metagenomics, personalized medicine, gene and epigenetic therapy of hereditary diseases.

Hormonal signalomics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Aim of discipline: to form the ability to analyze and explain the molecular genetic mechanisms of hormonal regulation of the vital activity of living organisms for research project development in the field of functional genetics. In studying the discipline, the following aspects will be addressed: physical and chemical fundamentals and structural organization of receptor-ligand ensembles taking part in hormonal response of the cell or living thing; modern views on hormonal classification, biosynthesis, and decomposition, molecular mechanisms of signaling effect of hormonal response in humans, animals and plants; hormonal signaling pathways, their extracellular, cytoplasmic and nuclear components; databases on hormonal signalomics and various hormonal crosstalks of eukaryotes; mapping of signaling hormonal cascades.

Innovative teaching technologies of genetics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to develop the ability to teach genetic disciplines, taking into account the integration of knowledge in the field of fundamental and applied research. The course examines: general pedagogical and specific principles of teaching; systems of methods, techniques, teaching aids in genetics; standard and innovative teaching methods, technologies for the development of critical thinking, modular, contextual and problem-based learning, online and distance learning, quality control of teaching.

Modern problems of human and animal genetics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Aim of discipline: to form the ability to analyze modern problems of human and animal genetics for the design of complex and interdisciplinary projects. In studying the discipline, the following aspects will be addressed: modern achievements of human and animal genetics, molecular, biochemical and cytological bases of genetic diseases; classification of forms of hereditary pathology; main genetic methods in the diagnosis of hereditary pathology; principles of treatment of hereditary diseases; prevention of hereditary diseases; study and applied use of new lines of model animal organisms as test systems.

Modern problems of plant genetics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Aim of discipline: to form the ability to modernize breeding-genetic and genetic engineering activities in agricultural centers. In studying the discipline, the following aspects will be addressed: the current state of plant genetics; objects and methods in plant genetics; plant cell engineering; somatic hybridization and its significance for the breeding process; cytoplasmic male sterility and the prospects for its use for breeding and genetic studies; chromosomal plant engineering; chromosomal technology in the crop breeding; molecular genetic mechanisms of plant morphogenesis; genetic engineering enzymes; DNA sequencing methods; genomic libraries; transgenic plants; decoding of the crop genome; plants as test systems.

Programming in Biostatistics
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to develop skills in statistical analysis using the R programming language, to deepen knowledge of methods for constructing probabilistic models, methods of statistical processing of multidimensional data. The course examines the study of the R programming language: the structure of the R language, functions, elements of functional programming, statistical data analysis and working with graphics in R; R packages; regression, analysis of variance.

Signalomics of eukaryotes
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to develop the ability to analyze the mechanisms of cellular signaling in eukaryotic organisms. The following will be considered: the main signaling pathways in eukaryotes (tyrosine kinase receptors, GPCRs, Wnt/β-catenin, Notch, NF-κB), signal transduction in the context of modern molecular biology, methods of signalomics research, the application of signalomics in interdisciplinary research, organization of relevant studies and models startups to commercialize signalomics.

Data for 2021-2024 years

INTERNSHIPS

Pedagogical
  • Type of control - Защита практики
  • Description - Formation of practical, educational-methodical skills of conducting lectures, seminars, creatively apply scientific, theoretical knowledge, practical skills in teaching activities, conduct training sessions in the disciplines of the specialty; own modern professional techniques, methods of training, use in practice the latest theoretical, methodological advances, make educational, methodological documentation.

Research
  • Type of control - Защита практики
  • Description - The purpose of the practice: gaining experience in the study of an actual scientific problem, expand the professional knowledge gained in the learning process, and developing practical skills for conducting independent scientific work. The practice is aimed at developing the skills of research, analysis and application of economic knowledge.

Data for 2021-2024 years