PhD program
Pharmaceutical Manufacturing Technology

Pharmaceutical Manufacturing Technology

QUALIFICATION

  • Scientific and pedagogical direction - Doctor of Philosophy (PhD)

MODEL OF GRADUATING STUDENT

1. Possess knowledge and modern innovative technologies for carrying out effective scientific and pedagogical activities, solving problems in the field of organizing the production of original medicines based on natural and synthetic raw materials, taking into account economic and environmental factors, their pharmacokinetics and bioequivalence.
2. Carry out targeted design of new pharmaceutical drugs based on computer and mathematical modeling, macromolecular polymer design, development of nanopharmaceuticals; comprehensive and complete identification of active pharmaceutical ingredients and drugs based on highly effective physicochemical methods.
3. Demonstrate the ability to organize, plan, and manage the activities of pharmaceutical organizations and enterprises in accordance with the current legislation of the Republic of Kazakhstan in the field of healthcare, Good Pharmaceutical Practices GxP (GMP, GLP, GSP, GDP, GPP), and principles of modern marketing and management.
4. Organize work to ensure and control the quality, safety, and efficacy of medicines, addressing identified violations of pharmaceutical activities in the production, storage, transportation, acceptance, and sale of medicines and medical devices in accordance with the current legislation of the Republic of Kazakhstan in the field of healthcare and Good Pharmaceutical Practices (GxP).
5. Organize systems of external and internal audits of entities engaged in pharmaceutical activities, demonstrating knowledge of Good Pharmaceutical Practices (GxP) and the current legislation of the Republic of Kazakhstan.
6. Analyze and control documentation related to the handling of medicines at all stages of their lifecycle: standard operating procedures, instructions, contracts, records, reports, test protocols, and other data.
7. Organize a system for monitoring, analyzing, and evaluating information on the safety of medicines in accordance with the current legislation of the Republic of Kazakhstan in the field of healthcare and Good Pharmacovigilance Practices (GVP).
8. Apply modern information and computer technologies in the collection, storage, processing, analysis, and transmission of professional information in the process of scientific and pedagogical activities at the university, as well as in production-technological, design-engineering, scientific-research, and organizational-management activities.
9. Carries out academic, research, scientific-methodological and social activities in the Higher Educational Institution.

Program passport

Speciality Name
Pharmaceutical Manufacturing Technology
Speciality Code
8D07201
Faculty
Chemistry and Chemical Technology

disciplines

Academic writing
  • Number of credits - 2
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to apply the skills and abilities in the field of written scientific communication necessary for effective communication in an academic environment. The discipline studies: features of communication in the scientific field; the main qualities of scientific speech; language features of scientific style; styles and genres of scientific works; structural types of texts; the development of speech culture; improving the level of literacy

Pharmacokinetics and bioequivalence studies: good clinical and laboratory practices
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to form a holistic understanding of pharmacokinetic studies of drugs in accordance with the requirements of Good Practices (GxP), all stages of bioequivalence studies, validation of methods for the quantitative determination of test substances in a biological matrix. The discipline forms the scientific and methodological basis of the concept of bioequivalence and methods of its implementation.

Regulatory requirements for the production of medicines
  • Number of credits - 5
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to implement standards of good pharmaceutical practices in pharmaceutical production. The discipline forms a theoretical and methodological basis for organizing pharmaceutical production in conditions of good pharmaceutical practices, is aimed at studying their international standards for conducting and controlling the process of development, production, release and circulation of medicines through the use of effective monitoring and control systems.

Scientific Research methods
  • Number of credits - 3
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - Purpose: to form the ability to apply modern methods and methodologies of scientific research when performing a doctoral dissertation. Here are considered: methods and methodologies of scientific research; modern experimental approaches to the scientific research of a doctoral student; stages and principles of planning a scientific experiment.

Data for 2021-2024 years

disciplines

Computer and mathematical modeling of medicines
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to use computer and mathematical modeling to develop new drugs and dosage forms, conduct their preclinical and clinical trials. The discipline forms the theoretical and methodological basis for the creation of new drugs, establishing their dosage regimen, optimal routes of administration, duration of treatment, their correction in case of ineffective treatment or poor tolerance by patients.

Current trends in the development of chemistry and technology for the production of herbal medicines
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to establish the chemical composition of plants and develop innovative technologies for the production of unique medicinal substances and preparations based on them. The discipline develops knowledge about the structure, chemical and biological properties of the active ingredients of substances, the selection of the most rational, economically and environmentally sound technologies for the production of herbal medicines, ensuring their biological safety and high efficiency.

Development of new and innovative polymer-based drug and biomaterial delivery systems
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose: to develop the ability to develop and analyze new and innovative delivery systems for drugs and biomaterials based on polymers, assessing their effectiveness, biocompatibility and functional properties. The discipline forms a theoretical and methodological basis for the design of polymer delivery systems, evaluation of properties and application in medicine and pharmaceuticals.

Highly effective physicochemical methods for identifying plant substances and preparations
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to identify the fine structure of the active substances of herbal medicinal substances and herbal remedies in various dosage forms using modern spectral and chromatographic methods. The discipline forms the theoretical and methodological basis for the methodology of research and identification of various drugs using UV, mass, 1H-NMR, 31C-NMR spectra, thin-layer, gas, gas-liquid and high-performance liquid chromatography methods.

Macromolecular design and functioning of biomedical polymers
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose: to develop the ability to apply the principles of macromolecular design to obtain multifunctional polymer materials for medical and biological purposes with the required set of properties. The discipline focuses on studying new and modern methods and technologies, the principles of polymer design, including the selection of monomers and synthesis methods used to create and analyze polymer materials with the desired properties.

Marketing and management in pharmaceutical production
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose: to develop the ability to create marketing strategies and plans, manage brands, and evaluate the effectiveness of marketing campaigns. The course is aimed at studying the fundamentals of marketing activities and management in the context of the pharmaceutical industry, the basic principles and methods of marketing research, strategies for promoting pharmaceutical products, market analysis, and the management of production and business processes in pharmaceutical companies.

Metabolic reactions and creation of prodrugs
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to explain the action of drugs based on metabolic reactions, to evaluate the products of transformation in the body to create prodrugs. The discipline forms a theoretical and methodological basis for the classification of reactions and metabolic conditions of pharmacophores of organic compounds, assessment of their stability in the body for the creation of prodrugs and principles for the development of new dosage forms.

Modern aspects of the development of nanomedicines
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose: to develop the ability to present a holistic system of theoretical foundations for development of nanomedicines, to apply the principles of pharmaceutical chemistry in the creation and assessment of the quality of nanomedicinal substances. The discipline examines modern achievements of fundamental chemical sciences and nanobiomedical technologies, sources and methods of obtaining biotechnological nanomedicinal substances, their physical and chemical properties, and the relationship of chemical structure with pharmacological properties.

Synthesis planning and creation of potentially biologically active compounds
  • Type of control - [RK1+MT+RK2+Exam] (100)
  • Description - The purpose of the discipline: to develop the ability to plan targeted synthesis of biologically active compounds, to evaluate options for constructing a given structure to optimize the method for obtaining a given substance. The discipline forms a theoretical and methodological basis for reasoned drawing up schemes for synthesizing the structure of a given biologically active substance based on methods of targeted design of new drugs (drug design), molecular modeling and virtual screening of biological activity.

Data for 2021-2024 years

INTERNSHIPS

Pedagogical
  • Type of control - Защита практики
  • Description - Formation of practical, educational-methodical skills of conducting lectures, seminars, creatively apply scientific, theoretical knowledge, practical skills in teaching activities, conduct training sessions in the disciplines of the specialty; own modern professional techniques, methods of training, use in practice the latest theoretical, methodological advances, make educational, methodological documentation.

Research
  • Type of control - Защита практики
  • Description - The purpose of the practice: gaining experience in the study of an actual scientific problem, expand the professional knowledge gained in the learning process, and developing practical skills for conducting independent scientific work. The practice is aimed at developing the skills of research, analysis and application of economic knowledge.

Data for 2021-2024 years